abstract：Background/Aims:The presence of invasion is a diagnostic criterion of early gastric cancer (EGC) in Korea, whereas diagnosis in Japan is based on enlarged nuclei and prominent nucleoli. Moreover, the depth of invasion is the location of cancer cell infiltration in Korea, whereas it is the location of lymphovascular inv...

journal_title：Gut and liver

authors： Lee SY,Yoshida N,Dohi O,Lee SP,Ichikawa D,Kim JH,Sung IK,Park HS,Otsuji E,Itoh Y,Shim CS,Han HS,Kishimoto M,Naito Y

更新日期：2017-05-15 00:00:00

abstract：Background/Aims:The benefit of oral antiviral therapy in preventing hepatocellular carcinoma (HCC) in the general population is not well understood. We used a novel prediction method to estimate the risk of HCC in the Korean population based on various treatment guidelines. Methods:The 5-year risk of HCC following ant...

journal_title：Gut and liver

authors： Shim JJ,Oh IH,Kim SB,Kim JW,Lee CK,Jang JY,Lee JS,Kim BH

更新日期：2016-11-15 00:00:00

abstract：Background/Aims:Helicobacter pylori is a major risk factor for atrophic gastritis (AG) and gastric cancer. The correlation between H. pylori, AG and colorectal neoplasm (CRN) has only been examined in a limited number of studies, and findings have been inconclusive. We aimed to investigate the association between H. py...

journal_title：Gut and liver

authors： Lee JY,Park HW,Choi JY,Lee JS,Koo JE,Chung EJ,Chang HS,Choe J,Yang DH,Myung SJ,Jung HY,Yang SK,Byeon JS

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND/AIMS:We evaluated the characteristics of the National Cancer Screening Program (NCSP) and opinions regarding the National Endoscopy Quality Improvement Program (NEQIP). METHODS:We surveyed physicians performing esophagogastroduodenoscopy and/or colonoscopy screenings as part of the NCSP via e-mail between J...

journal_title：Gut and liver

authors： Cha JM,Moon JS,Chung IK,Kim JO,Im JP,Cho YK,Kim HG,Lee SK,Lee HL,Jang JY,Kim ES,Jung Y,Moon CM,Kim Y,Park BY

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND/AIMS:The aim of this study was to evaluate the effect of the synthetic S-allyl-L-cysteine (SAC) PMK-S005 on gastric acid secretion, inflammation, and antioxidant enzymes in aging rats. METHODS:The rats were divided into four groups at 31 weeks of age and were continuously fed a diet containing a vehicle con...

journal_title：Gut and liver

authors： Choi YJ,Kim N,Lee JY,Nam RH,Suh JH,Lee SM,Ham MH,Jo HJ,Shim YK,Park YH,Lee JC,Choi YJ,Lee HS,Lee DH

更新日期：2016-09-15 00:00:00

abstract：:Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of bile volume and composition. They are also involved in damaging and repairing the liver. Cholangiocytes have many functions i...

journal_title：Gut and liver

authors： Yoo KS,Lim WT,Choi HS

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND/AIMS:Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surg...

journal_title：Gut and liver

authors： Lee JH,Park JM,Han SU,Kim JJ,Song KY,Ryu SW,Seo KW,Kim HI,Kim W,Korean Antireflux Surgery Study (KARS) Group.

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND/AIMS:Despite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion. We aimed to explore the potential efficacy of combination therapy consisting of pegylated interferon (p-IFN) and an oral antivira...

journal_title：Gut and liver

authors： Wi CI,Kim WR,Gross JB,Stadheim LM,Poterucha JJ

更新日期：2016-07-16 00:00:00

abstract：:Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic inflammatory conditions affecting the gastrointestinal tract with variable presentations and disease courses. The cause of IBD is unknown, but it is hypothesized that individuals with a genetic predisposition to disease deve...

journal_title：Gut and liver

authors： Raffals LE,Chang EB

更新日期：2016-07-15 00:00:00

abstract：BACKGROUND/AIMS:Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS:We retrospectively reviewed 68 patients with hilar NCC treated with either PDT plu...

journal_title：Gut and liver

authors： Wentrup R,Winkelmann N,Mitroshkin A,Prager M,Voderholzer W,Schachschal G,Jürgensen C,Büning C

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND/AIMS:Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors influencing the clinical course of ESD-related colon perforation. METH...

journal_title：Gut and liver

authors： Kang DU,Choi Y,Lee HS,Lee HJ,Park SH,Yang DH,Yoon SM,Kim KJ,Ye BD,Myung SJ,Yang SK,Kim JH,Byeon JS

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND/AIMS:Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma cell lines. METHODS:The human gastric adenocarcinoma cell lines AGS, KATO-III, MKN-45,...

journal_title：Gut and liver

authors： Kim JH,Park JJ,Lee BJ,Joo MK,Chun HJ,Lee SW,Bak YT

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND/AIMS:To determine factors predictive of discordance in staging liver fibrosis using liver biopsy (LB) and acoustic radiation force impulse (ARFI) elastography in patients with chronic hepatitis B (CHB). METHODS:Consecutive patients with CHB who underwent LB and ARFI elastography on the same day from Novembe...

journal_title：Gut and liver

authors： Park MS,Kim SW,Yoon KT,Kim SU,Park SY,Tak WY,Kweon YO,Cho M,Kim BK,Park JY,Kim DY,Ahn SH,Han KH

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND/AIMS:This study sought to characterize the current sedation practices of Korean endoscopists in real-world settings. METHODS:All active members of the Korean Society of Gastrointestinal Endoscopy were invited to complete an anonymous 35-item questionnaire. RESULTS:The overall response rate was 22.7% (1,332...

journal_title：Gut and liver

authors： Lee CK,Dong SH,Kim ES,Moon SH,Park HJ,Yang DH,Yoo YC,Lee TH,Lee SK,Hyun JJ,Korean Society of Gastrointestinal Endoscopy Task Force on Endoscopic Sedation.

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Ischemic colitis includes a wide clinical spectrum ranging from mild to severe forms. This study aimed to determine the factors that are related to the occurrence of severe ischemic colitis. METHODS:This multicenter study was conducted retrospectively in Korea. The patients were divided into mild and s...

journal_title：Gut and liver

authors： Choi SR,Jee SR,Song GA,Park SJ,Lee JH,Song CS,Park HU

更新日期：2015-11-23 00:00:00

abstract：:A systematic review (SR) provides the best and most objective analysis of the existing evidence in a particular field. SRs and derived conclusions are essential for evidence-based strategies in medicine and evidence-based guidelines in clinical practice. The popularity of SRs has also increased markedly in the field o...

journal_title：Gut and liver

authors： Kim G,Cho YZ,Baik SK

更新日期：2015-11-23 00:00:00

abstract：BACKGROUND/AIMS:The usefulness of immunohistochemistry to screen for the microsatellite instability (MSI) phenotype in gastric cancer remains unclear. Moreover, the prognostic value of MSI phenotypes in gastric cancer has been debated. METHODS:The clinicopathologic parameters and survival outcomes of 203 MSI-high (MSI...

journal_title：Gut and liver

authors： Bae YS,Kim H,Noh SH,Kim H

更新日期：2015-09-23 00:00:00

abstract：BACKGROUND/AIMS:In patients with corticosteroid-refractory ulcerative colitis (UC), cyclosporine or infliximab may be added to the treatment regimen to induce remission. Here, we aimed to compare the efficacy of cyclosporine and infliximab. METHODS:Between January 1995 and May 2012, the medical records of 43 patients ...

journal_title：Gut and liver

authors： Kim EH,Kim DH,Park SJ,Hong SP,Kim TI,Kim WH,Cheon JH

更新日期：2015-09-23 00:00:00

abstract：BACKGROUND/AIMS:M2 pyruvate kinase (M2-PK) is an enzyme that is produced in undifferentiated and proliferating tissues. This study aims to evaluate the usefulness of the immunochromatographic M2 pyruvate kinase (iM2-PK) for the screening of colorectal cancer (CRC) and premalignant lesions. METHODS:Healthy volunteers a...

journal_title：Gut and liver

authors： Kim YC,Kim JH,Cheung DY,Kim TH,Jun EJ,Oh JW,Kim CW,Chung WC,Kim BW,Kim SS,Kim JI,Park SH,Kim JK

更新日期：2015-09-23 00:00:00

abstract：BACKGROUND/AIMS:Drug-induced liver injury (DILI) is a frequent cause of pediatric liver disease; however, the data on DILI are remarkably limited. METHODS:All 69 children hospitalized with DILI between January 2009 and December 2011 were retrospectively studied. RESULTS:A total of 37.7% of the children had medical hi...

journal_title：Gut and liver

authors： Zhu Y,Li YG,Wang JB,Liu SH,Wang LF,Zhao YL,Bai YF,Wang ZX,Li JY,Xiao XH

更新日期：2015-07-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide. This cancer commonly arises against a background of chronic liver disease. As a result, a patient with HCC requires multidisciplinary care. Treatment options vary widely based on tumor burden and metastases. The most widely utili...

journal_title：Gut and liver

authors： Au JS,Frenette CT

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND/AIMS:Several precut techniques have been used to gain biliary access for difficult cases. The aim of this study was to evaluate the success and complication rates of two precut techniques, transpancreatic septotomy (TPS) and needle knife infundibulotomy (NKI), in difficult biliary cannulation due to the pres...

journal_title：Gut and liver

authors： Lee YJ,Park YK,Lee MJ,Lee KT,Lee KH,Lee JK

更新日期：2015-07-01 00:00:00

abstract：:The guideline for the management of hepatocellular carcinoma (HCC) was first developed in 2003 and revised in 2009 by the Korean Liver Cancer Study Group and the National Cancer Center, Korea. Since then, many studies on HCC have been carried out in Korea and other countries. In particular, a substantial body of knowl...

journal_title：Gut and liver

authors： Korean Liver Cancer Study Group (KLCSG).,National Cancer Center, Korea (NCC).

更新日期：2015-05-23 00:00:00

abstract：BACKGROUND/AIMS:Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, sev-eral cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clini-cal, and histopa...

journal_title：Gut and liver

authors： Park HS,Han DS,Ro YO,Eun CS,Yoo KS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND/AIMS:There has been a lack of research comparing balloon dilatation and self-expandable metal stent (SEMS) placement to determine which is better for long-term clinical outcomes in patients with benign colorectal strictures. We aimed to compare the clinical efficacy and complication rates of balloon dilatati...

journal_title：Gut and liver

authors： Park CH,Yoon JY,Park SJ,Cheon JH,Kim TI,Lee SK,Lee YC,Kim WH,Hong SP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate the association between the baseline profiles and dynamics of hepatitis B virus (HBV) DNA polymerase gene mutations and the long-term virological response of lamivudine (LAM)-adefovir (ADV) combination therapy in patients with LAM-resistant chronic hepatitis B. METHODS:Seventy-five patie...

journal_title：Gut and liver

authors： Kim J,Lee SH,Kim HS,Choi K,Jeong SW,Kim SG,Jang JY,Kim YS,Kim BS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Second-look endoscopy is performed to check for the possibility of post-endoscopic submucosal dissection (ESD) bleeding and to perform prophylactic hemostasis in most hospitals; however, there is little evidence about the efficacy of second-look endoscopy. We investigated whether second-look endoscopy a...

journal_title：Gut and liver

authors： Kim ER,Kim JH,Kang KJ,Min BH,Lee JH,Rhee PL,Rhee JC,Kim JJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The quality of bowel preparation (QBP) is the important factor in performing a successful colonoscopy. Several factors influencing QBP have been reported; however, some factors, such as the optimal preparation-to-colonoscopy time interval, remain controversial. This study aimed to determine the factors ...

journal_title：Gut and liver

authors： Kim TK,Kim HW,Kim SJ,Ha JK,Jang HH,Hong YM,Park SB,Choi CW,Kang DH

更新日期：2014-11-01 00:00:00

abstract：:A 75-year-old Japanese man with chronic hepatitis C was found to have a large liver tumor and multiple nodules in the bilateral lungs. We diagnosed the tumor as hepatocellular carcinoma (HCC) with multiple lung metastases based on imaging studies and high titers of HCC tumor markers. Remarkably, without any anticancer...

journal_title：Gut and liver

authors： Saito T,Naito M,Matsumura Y,Kita H,Kanno T,Nakada Y,Hamano M,Chiba M,Maeda K,Michida T,Ito T

更新日期：2014-09-01 00:00:00

abstract：:The combination of pegylated interferon (PEG-IFN) and ribavirin (RBV), the current therapy for hepatitis C virus (HCV) infection, has saved the lives of many HCV-infected patients. Direct-acting antivirals (DAAs) target several sites of HCV nonstructural proteins, resulting in the cessation of viral replication. The f...

journal_title：Gut and liver

authors： Kim DY,Ahn SH,Han KH

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND/AIMS:High intensity focused ultrasound (HIFU) utilizes a targeted extracorporeal focused ultrasound beam to ablate neoplastic pancreatic tissue. We used an in vitro model to examine the effects of bone, metallic stents, plastic stents, metal plates, and cyst-like lesions on HIFU treatment. METHODS:HIFU was ...

journal_title：Gut and liver

authors： Hassanuddin A,Choi JH,Seo DW,Ryu CH,Kim SH,Park DH,Lee SS,Lee SK,Kim MH

更新日期：2014-07-01 00:00:00

abstract：:Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), whose incidence has increased sharply in the last 4 decades. The annual conversion rate of BE to cancer is significant, but small. The identification of patients at a higher risk of cancer therefore poses a clinical conundrum. Cur...

journal_title：Gut and liver

authors： di Pietro M,Alzoubaidi D,Fitzgerald RC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND/AIMS:Patients with cholangiocarcinoma usually present at an advanced stage, and more than 50% of cases are not resectable at the time of diagnosis. Recently, photodynamic therapy (PDT) has been proposed as a palliative and neoadjuvant modality. We evaluated whether combination of PDT and chemotherapy is more...

journal_title：Gut and liver

authors： Hong MJ,Cheon YK,Lee EJ,Lee TY,Shim CS

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND/AIMS:Knowledge of the risk factors associated with adverse outcomes after percutaneous endoscopic gastrostomy (PEG) may be helpful for developing PEG recommendations. The purpose of this study was to identify the clinical risk factors associated with adverse clinical outcomes after PEG, especially regarding ...

journal_title：Gut and liver

authors： Im JP,Cha JM,Kim JW,Kim SE,Ryu DY,Kim EY,Kim ER,Chang DK

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND/AIMS:α-Fetoprotein (AFP) is the biomarker most widely used to detect hepatocellular carcinoma (HCC), despite its suboptimal diagnostic accuracy. Glypican-3 (GPC3) and osteopontin (OPN) are secreted glycoproteins that are reportedly associated with tumorigenesis and metastasis. This study was conducted to eva...

journal_title：Gut and liver

authors： Lee HJ,Yeon JE,Suh SJ,Lee SJ,Yoon EL,Kang K,Yoo YJ,Kim JH,Seo YS,Yim HJ,Byun KS

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND/AIMS:As the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with hospital-acquired diarrhea (HAD). This study focused on identifying the clinical risk factors that can easily predi...

journal_title：Gut and liver

authors： Yang BK,Do BJ,Kim EJ,Lee JU,Kim MH,Kang JG,Kim HS,Kim KH,Jang MK,Lee JH,Kim HY,Shin WG

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study was performed to determine the association between RUNX3 expression and Helicobacter pylori infection in premalignant gastric lesions. METHODS:We examined 107 patients with gastric epithelial dysplasia who had undergone endoscopic mucosal resection or submucosal dissection. All tissue sample...

journal_title：Gut and liver

authors： Chung WC,Jung SH,Joo KR,Kim MJ,Youn GJ,Kim Y,Lee JS,Lee H,Jung JH,Lee YK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND/AIMS:Small core biopsy samples can occasionally be obtained with conventional endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). Although most studies have focused on the cytological analysis of specimens, data regarding histological assessment is scarce. The aim of this study was to determi...

journal_title：Gut and liver

authors： Kim TH,Choi KH,Song HS,Kim JW,Jeon BJ

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND/AIMS:Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to ...

journal_title：Gut and liver

authors： Yamada E,Ohkubo H,Higurashi T,Sakai E,Endo H,Takahashi H,Uchida E,Tanida E,Izumi N,Kanesaki A,Hata Y,Matsuura T,Fujisawa N,Komatsu K,Maeda S,Nakajima A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND/AIMS:To investigate the incidence of cholangiocarcinoma in patients with hepatolithiasis with or without previous resection of liver. METHODS:From 2002 to 2009, we retrospectively reviewed 117 patients who were diagnosed and treated for hepatolithiasis in Korea University Guro Hospital. Among the 117 patien...

journal_title：Gut and liver

authors： Lee JY,Kim JS,Moon JM,Lim SA,Chung W,Lim EH,Lee BJ,Park JJ,Bak YT

更新日期：2013-07-01 00:00:00